Spider-Man: Brand New Day

Spider - Man ’s rogues art gallery in Marvel Comics includes some of the most iconic , well - known and popular villain in risible book history , some of whom have already been conform for the live - activity MCU . So far , Spider - Man has battle the Vulture , Mysterio , Thanos and threats from across the multiverse , including the likes of the Green Goblin , Doctor Octopus , Lizard , Sandman and Electro . However , there are many moreSpider - Man villains that have n’t come out in the MCU , so it would be brilliant to see Peter Parker take on these young antagonists inSpider - Man 4 .

8Carolyn Trainer’s Lady Octopus

Lady Octopus Debuted In Marvel Comics In 1995’s The Amazing Spider-Man #406

While Otto Octavius ' Doctor Octopus has already look in the MCU in the form ofAlfred Molina ’s returningSpider - humanity 2villain , it ’s potential thatSpider - Man 4could have a different version of the eight - limbed villain . Carolyn Trainer was Octavius ' protégé in Marvel Comics , and became his replacement as Doctor Octopus follow his death in the Clone Saga in the nineties . She was originally Doctor Octopus II , but became Lady Octopus after Octavius ' resurrection , and she ’d make a fantastic villain for Peter Parker in the hot - action MCU .

Doctor Octopus is one ofSpider - Man ’s most notable villains , but since he has already appeared inSpider - Man : No Way house , it ’s probable that Marvel Studios will elect not to reliably adapt Otto Octavius again in the MCU ’s master persistence . Carolyn Trainer could take up the mantel , given her status as Octavius ' scholar in Marvel Comics , and an adaption of the Clone Saga has been excogitate for the MCU . Recently , Lady Octopus has become a extremity of the multiversal Sinister Squadron , a team that opposed the Spider Societyand would make a dandy mountain of sensory faculty in the MCU ’s Multiverse Saga .

7Mister Negative

Mister Negative Debuted In Marvel Comics In 2007’s Free Comic Book Day: The Amazing Spider-Man #1

There has been a with child deal of speculation concerningMister Negative ’s bouncy - action debut for several years , andSpider - Man 4would be a fantastic shoes to take the iconic street - degree villain into the MCU.Originally a mobster and human vendor , the man who would become Mister Negative was captured and subject to experiments alongside the future Cloak and Dagger . This granted him memory access to both Darkforce and Lightforce , and go to the emergence of two wildly unlike personality : philanthropist Mister Positive and crime boss Mister Negative .

Mister Negative ’s healing , mind control and Energy Department - charging abilities , as well as his superhuman force and reflexes , make him one of Spider - Man ’s most powerful villain . He has also taken on the like of Cloak and Dagger , the Punisher and Shang - Chi , so it would be great to bring in him to thestreet - level stories of the MCU.Daredevil : Born Againhas shone a light on the criminal underworld of the MCU , and Mister Negative could debut to become one of the key players in this unwell and gritty human beings inSpider - Man 4 .

6Miles Warren’s Jackal

The Jackal Debuted In Marvel Comics In 1965’s The Amazing Spider-Man #31

While Miles Warren set off his Marvel Comics life history as one of the least - popular members of Spider - Man ’s rogues verandah , the Jackal has gone on to become one of the wall - ass-kisser ’s most far-famed opposer . This was most predominant during the Clone Saga , which saw the Jackal clone Peter Parker and created Ben Reilly , Kaine Parker and more . mile Warren was also far-famed due to his obsession with Gwen Stacy , Parker ’s first love interest , who has been heavily rumored to be make her MCU debut inSpider - Man 4 , perhaps explainingSadie Sink ’s late casting in the sequel .

While Mary Jane Watson has choke on to become Spider - Man ’s independent love interest and even married woman , Gwen Stacy was Peter Parker ’s first romantic interest following his graduation from high school day until her death at the hands of the Green Goblin .

It ’s surprising that Miles Warren ’s Jackal has never been adapted into live - action before now . Over the 60 years since his Marvel Comics launching , he has become one of Spider - Man ’s most iconic villains , soSpider - Man 4would gain by bringing the genetically - raise scoundrel into the MCU , specially if this happens alongside Gwen Stacy . 2011’sSpider - Islandevent , orchestrated by the Jackal , has also been speculated to be conform for the MCU ’s Multiverse Saga , soSpider - Man 4might be the only and good fortune to bring Miles Warren into live - action mechanism .

Spider-Man in the MCU with Spider-Queen and the Jackal in Marvel Comics

Custom Image by Kai Young

5Charlotte Witter’s Spider-Woman

Charlotte Witter’s Spider-Woman Debuted In Marvel Comics In 1999’s The Amazing Spider-Man (Vol. 2) #5

In Marvel Comics ' persistence , Charlotte Witter was the quaternary quality to take up the mantle of Spider - Woman , though her version was far from a hero . Witter is the granddaughter offamed clairvoyant mutant Madame Web , and she was fecund in black market proceedings , which led her to work on with Doctor Octopus . Octavius mutated Witter into a human - spider cross in return for her match to down Spider - Man , and this phylogeny allows her to steal the ability of the former Spider - Women , though she was defeated by Mattie Franklin ’s loop of the spider - themed hero .

Spider - Women in Marvel Comics

Debut Issue

Steven Yeun in Minari with Marvel Comics' Amdaeus Cho Hulk and The Beyonder at each side

class

Jessica cast

Marvel Spotlight # 32

Zendaya’s MJ and Tom Holland’s Spider-Man looking sad in No Way Home

1977

Julia Carpenter

mysterious Wars # 6

Aaron Taylor Johnson as Sergei in Kraven the Hunter (2024) next to artwork of the character from Marvel Comics

1984

Mattie Franklin

The Spectacular Spider - Man # 262

Headshot Of Tom Holland In The 29th Annual Critics Choice Awards

1998

Charlotte Witter

The Amazing Spider - Man ( Vol . 2 ) # 5

Headshot Of Zendaya In The Los Angeles Premiere Of Amazon MGM Studios' ‘Challengers’

1999

Veranke ( posing as Jessica Drew )

New Avengers # 1

Headshot Of Jacob Batalon

2005

4Felicia Hardy’s Black Cat

Black Cat Debuted In Marvel Comics In 1979’s The Amazing Spider-Man #194

Perhaps the most - rumored character gestate to debut alongside Tom Holland ’s Peter Parker inSpider - Man 4has beenFelicia Hardy , a.k.a . the villain - turn - antihero known as Black Cat . After everyone in the world forgot Parker inSpider - Man : No Way place , including Zendaya ’s MJ , now is the perfect time to introduce a new lovemaking interest for the wall - crawler , and Black Cat is one of the most interesting . She is also one of the most knock-down , as she has the ability to manipulate chance landing field , give her enemy forged luck , whichDeadpool 2already test is a tycoon that works well on - screen .

The story of Tom Holland ’s Spider - Man 4 has been disclose , and it makes it easy for Zendaya ’s MJ to be replaced as Peter Parker ’s love interest .

Black Cat was almost played by Anne Hathaway in Sam Raimi’sSpider - Man 4 , made her live - action debut with Felicity Jones ' face inThe Amazing Spider - Man 2and almost took part in a live - activity series focused on Black Cat and Silver Sable . After these call off or lusterless personification , it would be keen to see Black Cat finally get a substantive function in live - action mechanism . No Way Homecreated a void that would makeFelicia Hardy ’s first appearance inSpider - Man 4very poignant and perfectly time , and she could become a new long - running frenemy to Tom Holland ’s hero .

Headshot Of Sadie Sink

3Morlun

Morlun Debuted In Marvel Comics In 2001’s The Amazing Spider-Man (Vol. 2) #30

Morlun is recognized as one of the most powerful and dangerous adversaries , not just of Peter Parker ’s Spider - Man , but of every variant of the wall - angleworm from across the multiverse . Morlun and his vampiric family , the Inheritors , jaunt from existence to universe to hunt Spider - Totems , which means he would fit perfectly into the MCU ’s Multiverse Saga , peculiarly since Morlun is the main antagonist of Marvel Comics’Spider - Verseevent . It would make a lot of sense forSpider - Man 4to explore the Spider - Verse in live - activity , soMorlun is utterly primed to be the sequel ’s villain .

Spider - Man : No direction Home’svillain - packed storylinehas leave big shoes forSpider - homo 4’santagonist to fill , as whoever takes the role needs to fork out more intensity and a bigger menace . Morlun is the perfect candidate to fill up this role , as he is perhaps the most persistent antagonist to every Spider - Man in Marvel Comics . He is a brutish and violent killer whale , so Morlun would be an incredibly dingy increase toSpider - Man 4 , but this might be just what the moving-picture show postulate , as his unveiling could even signify Peter Parker battling and get the better of his own darkness .

2Adriana Soria’s Spider-Queen

Spider-Queen Debuted In Marvel Comics In 2004’s Spectacular Spider-Man (Vol. 2) #15

As previously mentioned , theSpider - Islandstoryline has been the reservoir of speculation concerningSpider - Man 4’snarrative . If this comes to realization , Marvel Studios must introduce Adriana Soria , a.k.a . the herculean Spider - Queen , into live - activity . Soria was the first female United States Marine to go into fight during WWII . During fight , she absorbed actinotherapy from nuclear tests that drove her harebrained and activated latent abilities in her genes . She return to New York as " The Queen , " with her power enabling her to curb insects and give spider - like powers to those uncover to her saliva , which also eventually transformed her victim into spider - monsters .

Everyone in Manhattan received wanderer - similar great power during theSpider - Islandevent , which would be great to see in the MCU ’s Phase 6 .

This power set aside her to put Peter Parker under her ascendency , though she was originally bested . Later , however , she team up up with the Jackal to infect the residents of New York with the " Spider - Flu , " award them their own spider - like powers . TheSpider - Islandstoryline would make for a hard narrative inSpider - Man 4 , and the Spider - Queen is the best possible supervillain to debut in this outcome . Adriana Soria could change the landscape of the MCU eternally , and leave Peter Parker with his most acute and dangerous adversary yet .

Thunderbolts (2025) Official Poster

1Sergei Kravinoff’s Kraven The Hunter

Kraven The Hunter Debuted In Marvel Comics In 1964’s The Amazing Spider-Man #15

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Aaron Taylor - Johnson lately brought Sergei Kravinoff to life in 2024’sKraven the Hunter , but after the SSU movie ’s monumentally - bad box office performance and misfortunate reception , there have been calls for Marvel Studios to hastily reinvent the character for the MCU proper . Kraven the Hunter is one of Spider - Man ’s most iconic villain , typically a hunter who consider Spider - Man to be"the most dangerous game . “In his legendary 1987 plot line , Kraven ’s Last Hunt , the hunter even succeed in kill Spider - Man and lead his place , though the wall - crawler is soon revealed to have survived .

Kraven the Hunter is the next Spider - Man role to be part of Sony ’s Spider - Man Universe , stark with some change to his comic volume story .

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Kraven the Hunter is one of Spider - Man ’s oldest and most redoubtable foes , so he deserves far more military action in live - action mechanism than just the disappointing movie in Sony ’s Spider - Man Universe . There have been several mentions of him almost joining the MCU in late project , most notably in Ryan Coogler’sBlack Panther , butSpider - human being 4could finally make this a reality . A unrecorded - natural process battle betweenSpider - Man and Kraven the Hunterhas been extremely anticipated for years , so this would be an unbelievable selling head forSpider - military personnel 4 , and would aid to gloss over Sony ’s late Marvel movie mistakes .

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Spider-Man: Brand New Day

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