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Harley Quinnfights some very powerful baddie in her HBO Max animated series , include most of Batman ’s Rogues Gallery . She conduct on the strong and impudent in DC Comics as well , carving out a unequaled way as an anti - heroine who started off working for DC ’s not bad scoundrel to becoming a complex character with her own moral code .
Harley ’s war with the Joker dominates her plot line in the comics , but she fight many other villains as well . She also fights legion hero , includingBatman . But her biggest opposition often proves to be herself . Harley ’s heart always seems to be in the right position , but she often puts herself in terrible post that menace to weaken the extraordinary growth she ’s made in the thirty years since her entry .
Minor Disaster
Minor Disaster , also known as Penny Booker , fundamentally sought to become an influencer in the DC Universe . She did so by trying to fight back and vote out Harley Quinn in a live stream using her Disaster Dial , engineering science that affects probability by spin the top . This pick set out considerably , tear down the playing field for any opponent .
Minor Disaster , the girl of supervillain Major Disaster , nearly destroy Coney Island in her battle with Harley . But Harley ’s empathy for her , despite their animus , facilitate Booker change her view on being a villain .
Hugo Strange
Harley fights Hugo Strange in a late plot line from 2021 . unknown , amongBatman ’s most underrated villains from the funnies , have incredible brilliance and a cruel intent to use it . He proves a master of manipulation , which is especially grievous for Harley , who has march in the past she ’s susceptible to this .
unusual also makes for a powerful Harley Quinn villain because both are psychiatrist . Though she in general seek only to avail hoi polloi understand themselves , Strange uses his insights to exploit citizenry .
Punchline
Harley Quinn issue as an instant icon in " Joker ’s Favor , " amongthe most definitiveBatman : The Animated Seriesepisodes . She revolutionise many ape and in some regard Punchline fit the bill . Punchline arguably carves her own identity by being a far - more cutthroat and ruthless lackey for the Joker .
Punchline display warlike nontextual matter skills far in improvement of Harley and a facility with deadly weapons , including matching dagger she used to cut Harley ’s cervix with . She also proves much more logistically able and set than Harley ever was in the Joker ’s Gang .
Batgirl
Batgirl numbers amongthe good soldierlike artists in the DC Universe , bringing a racy knowledge of dissimilar fighting styles and weapons to her struggle with Harley Quinn . She also possesses remarkable adroitness with technology and news assemblage she develop during her clip as Oracle .
Batgirl also seldom fights solo as a extremity of the expectant Bat - Family , which includes numerous heavy - hitters like Nightwing and Batwoman . Batgirl and Harley often adjoin heads in the comics , let in Harley ’s very first comic Holy Writ , The Batman Adventures#12 , but they ’ve been allies as well in a phone number of different escapade .
Batman
Batman order among Harley ’s most powerful villains thanks to his many extraordinary talent . arm with numerous imaginative weapons and nearly innumerous money , Batman bring an entire high-pitched - tech armoury against any opposition , as well as superior fight and detective skills that untie the most elaborate system .
Harley and Batman often clash in the comics but also determine themselves on the same side sometimes . InWhite Knight , amongthe best Batman risible book storylines , a Harley variant falls in love with Batman in a universe where Joker became a hoagie .
Amanda Waller
Amanda Waller brings her considerable intelligence agency and lethal efficiency to draw Task Force X and the Suicide Squad . She rules the government - run team with an iron clenched fist , and a willingness to down , make her a powerful villain for Harley , though they worked together on many delegation for the greater respectable when Harley serve well on the team .
Waller refuses to take no for an solvent , a challenge for Harley , whose effusive personality tend to steamroll other citizenry . The two collide legion fourth dimension in the comic strip both in unconstipated DC Comics continuity and also in Injustice 2 , and it often take all of Harley ’s wit to get away .
General Zod
General Zod possess all the power Superman does , admit superhuman strength , speed , and stamina . He can fire laser - electron beam from his eyes and fly extremely fast thanks to his Kryptonian physiology , at least when he ’s near a yellowed sunlight . He lacks Superman ’s humanity and value-system , making him even more dangerous .
Zod and Harley come in to blows when Zod chance captured by the Suicide Squad . He hold the full range of his powers against the squad , leading to a cataclysmic fight in which Rick Flagg loses his life trying to quit the villain .
The Joker
The Joker top the list when it comesBatman ’s most evil comical book villainsand in many respect he does the same with Harley . Though he miss any superpowers , his ability to gaslight , diminish , and control others , specially Harley , makes him especially dark . He stole her self-respect and agency , though she was a willing spouse in some respects .
Joker ’s lethal disregard for others and desperate demand to incite chaos makes him fabulously muscular and in his own room enticing , a toxic mix for Harley as has been limn in various comic , animated series , and the movies . She struggles to say no to him , which he work again and again .
Herself
As her friend and lover Poison Ivy often tells her , Harley Quinn has everything going for her . Harley possess cracking insight into people , thick wells of empathy , and a limitless capacity to help others even if sometimes thing bend out bally . But Harley work against herself as well , sell herself short and denying her own delegacy and powerfulness .
Harley issue as an icon for many buff in the comics and other media thanks to her noteworthy narrative arc , escape the Joker ’s clasp to chart her own path . This remains her dominant feature but as late strip , display , and movies have shown , it ’s always under menace from her own insecurity and lack of self - worth .
